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Cons: When you take T4 alone, the body needs to convert (activate) it to T3

benefit-risk assessment critical

ApoE2 and ApoE3 bind preferentially to small phospholipid-rich HDL, while ApoE4 is found to bind preferentially to large triglyceride-rich VLDL (Nguyen et al., 2010)

Its important to discuss these challenges with a healthcare provider who can help you manage your condition while also considering its impact on your quality of life, including your sexual health