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The basic yet effective idea behind fat-dissolving medications like Kybella and PCDC is that they specifically target and destroy fat cells in certain regions

Polycomb group protein ezh2 controls actin polymerization and cell signaling

HFD could also promote the overgrowth of pathogenic bacteria in the intestine and induce the maturation of proinflammatory immune cells, leading to uncontrolled inflammation and mucosal damage indirectly, which were unable to inhibit the overgrowth of pathogenic bacteria, further aggravating the pathophysiological state (Statovci et al., 2017)

The lung is one of the organs where these damages are most common

Endophytic halotolerant Bacillus velezensis FMH2 alleviates salt stress on tomato plants by regulating ion accumulation (decreased endogenous Na + accumulation, increased K + and Ca 2+ uptake) and enhancing antioxidant responses (Masmoudi et al., 2021)