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Description

It has narrow tight- junctions, no fenestrae, low pinocytotic activity and a continuous basement membrane

This is why older patients should receive a reduced dosage of the drug ( 6.2 Strategies to increase bioavailability of taxanes 6.2.1 Nanoformulations Paclitaxel is administered intravenously and has low water solubility

However, further studies involving more extensive single-cell evaluations are essential, given the limited scope of cells analyzed in these studies (85)