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This cross-cutting deficit may be a key contributor to a wider range of striatum-mediated decision-making abnormalities seen in both conditions at a behavioral level

Sequences targeting GCDH (RefSeq ID: 2639) were identified using VBC-Score, and the top three hits were cloned into the pKLV-U6sgRNA pGK Puro-2A-BFP vector (Addgene, 50946) using BbsI cloning

CBP/p300 is a transcriptional coactivator protein with acetyltransferase activity

doi: 10.1016/j.ccell.2024.08.011 85 YangDLiuJQianHZhuangQ

Intravenous vitamin therapy infuses a combination of nutrients directly into the bloodstream, which bypasses the digestive system and allows the vitamins and minerals to be absorbed into the body quickly