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Since the liver is the major site of IGF-1 production, when steatosis develops lowering insulin sensitivity, the severity of steatosis at different stages of insulin resistance and metabolic syndrome seems to be correlated with worsened circulating IGF-1 levels [234]

Key Takeaways: What Tesamorelin Actually Does to Appetite and Body Composition Tesamorelin does not directly suppress appetite

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It is important to have a physician evaluate these symptoms so that appropriate medical care can be given.