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Adjusting the Normal Dose of B12 Injection for Severe Cases For severe vitamin B12 deficiency, higher doses might be needed to quickly fill up body stores

DIOSynVaxs approach is a viral-genome-informed method that creates an antigen sequence that is as similar as possible to all inputted sequences from a phylogenetic perspectivein this case, representative sequences for all known sarbecoviruses

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In these cases, a maintenance injection is often needed every 2-3 months to keep levels stable, as the body cant consistently source it otherwise

The lyophilized vial itself should be held at -20C for long-term stability