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Glantz, A

Cell cycle analysis Cells were seeded at a density of 0.5 10 6 per well in a six-well plate

Vn ng thng xuyn o thi c t cho da, gip da hng ho

Clin Pract (2020) 10(2):1271

However, in some metabolic disorders, Parp2 -knockout mice showed enhanced SIRT1 activity and improved metabolic functions, and were protected against high-fat diet-induced obesity, which were not due to augmented NAD + levels, but to an increase in SIRT1 expression, as PARP2 acts as a direct negative regulator of the SIRT1 promoter [59]