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2 Results 2.1 Pharmacokinetic studies of BPC157 in rats The effective dose of BPC157 for the treatment of various injuries in mice, rats, and rabbits ranges from 6 to 50 g/kg ( The mean (+SD) plasma concentration of BPC157 versus time curves following administration of various BPC157 doses in rats are shown in Figures 1AC, and the corresponding pharmacokinetic parameters are presented in Tables 1Tables 3

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BPC-157 supports this interconnected system by: Strengthening tight junctions between intestinal epithelial cells, reducing intestinal permeability (leaky gut) Modulating the enteric nervous system to normalize motility and reduce visceral hypersensitivity Regulating mucosal immune responses to prevent inappropriate inflammation against dietary and microbial antigens Conditions Treated with Oral BPC-157 Beyond Symptom Relief: Addressing Root Causes Unlike proton pump inhibitors (PPIs) that suppress stomach acid or corticosteroids that broadly dampen immunity, BPC-157 works by restoring the underlying structural and functional integrity of the gastrointestinal tract