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As ROS are a known inhibitor of mTOR activation, they showed that intracellular GSH was able to buffer ROS leading to mTOR activation, metabolic reprogramming, and resultant inflammatory response of T cells in vitro and in vivo (45)

However, studies also show that while autophagy may contribute to death signaling in neurons, it simultaneously acts as a mechanism to continuously monitoring the cells survival state

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2.1.3.7 TCM for diabetic retinopathy A meta-analysis of elderly patients with diabetic retinopathy (DR) identified three clinical studies involving Danhuang Mingmu Decoction and Zhenwu Decoction (34)