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(2013) also reported that hyperosmolarity inhibited the viability, proliferation, and expression of SOX-9, aggrecan, and collagen II in NP-MSCs and NPCs, but NP-MSCs exhibited stronger tolerance than NPCs
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Exposure to high oxygen pressure is known to cause hyperoxic lung injury characterized by increased ROS generation and the production of pro-inflammatory cytokines such as IL-8 and IL-1
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