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Reithmeier showed in 1987 that the structure of another calcium-binding protein, calsequestrin (which binds 40-50 calcium ions and is characterized by high levels of acidic residues), is calcium-sensitive as well, as this protein was rapidly degraded by trypsin in the absence of calcium, but showed remarkable stability in calcium-loaded form (Ohnishi and Reithmeier, 1987)

However, there are many commonly known signs of this vitamin deficiency you should be on the lookout for

doi: 10.1210/jcem.85.1.6321 63 FazeliPKKlibanskiA

CPT and Level II HCPCS code changes that affect the OPPS are published through the annual rulemaking cycle and through the OPPS quarterly update Change Requests (CRs)

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