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PCA analysis based on the metabolomic state revealed distinct clustering of the two cohorts, suggesting a distinct metabolic BM microenvironment in LTR compared to STR (Fig

We measured the Cdc42 activity using a biochemical assay based on the rationale that the active form of Cdc42 binds to the p21-binding domain (PBD) of p21-activated kinase 1 (PAK) with a high affinity (Zhang et al, 1998)

159,160 MUTYH is a 60 kDa glycosylase that comprises 546 amino acids, including twelve Cys residues

Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW (2014) Sulforaphane treatment of autism spectrum disorder (ASD)

Wang X, Liu J, Wang Z, et al