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In addition to the gut-brain and gut-kidney axes, the gut microbiota systemically communicates through other axes such as the gut-liver (Albillos et al., 2020), gut-heart (Zhao et al., 2023), gut-skin (Sinha et al., 2021), and gut-bone (Zhang et al., 2024) axes, among others

At the apical membrane, carnitine is transported inside the cell via the sodium-coupled carnitine transporter SLC22A5 (OCTN2) (40)

When data were not normally distributed the non-parametric tests such as the Mann-Whitney U-test or KruskalWallis analysis of variance were used

Though lowering serum uric acid may help prevent incident and recurrent gout, more studies are needed to test this possibility

doi: 10.3390/ijms22126493 54 BillesblleCBAzumayaCMKretschRCPowersASGonenSSchneiderSet al