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This research-grade compound is supplied as a lyophilised (freeze-dried) powder , designed to ensure stability, precision, and reproducibility in controlled scientific environments

The tripeptide enters cells via PepT1 transporter and reduces pro-inflammatory cytokine secretion in intestinal epithelial cells and macrophages[14]

The disadvantage is that higher doses require large injection volumes

To illustrate, a 2015 study showed that rats fed a collagen peptide absorbed more than 63% of the collagen, whereas other orally administered peptides have exhibited bioavailability rates as low as 1-2%.12 13 BPC-157 is an exception, too it remains stable in gastric juice for more than 24 hours, allowing it time to pass through the gastrointestinal walls15 but its often used in conjunction with the not-so-orally-bioavailable TB4

A separately prepared extraction mixture (5 ml), consisting of Acetonitrile: 5 mM ammonium acetate (6:4 v/v, pH 3.5), was added to the mentioned prepared samples followed by shaking (20 min at 100 rpm) using a reciprocating shaker