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J Biol Chem (2014) 289(46):3177791

Exosomes from mesenchymal stromal cells were able to up-regulate the expression of MT-2, elevate the transcriptional level of IB in macrophages of mice with colitis, and inhibit the activation of NF-B

2024;10(13):eadm9859

This depends on a number of factors: The bacteria you choose How you wish to store the product Whether the formulation is designed to ensure the probiotics reach the part of the digestive system where they are needed