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Another modification of the method is Raman optical activity (ROA) that detects chiral molecules by measuring a small difference in their vibrational Raman scattering intensity when illuminated with right- and left-circularly polarized light (incident circular polarization, ICP) (Zhu et al., 2005)

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It reflects the half-life degradation curve of alpha-melanocyte-stimulating hormone (-MSH) analogs in aqueous solution at refrigeration temperature

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