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10.1371/journal.pgen.1007947 354 WangW

Statistical significance between pairs of groups was assessed using an unpaired two-sided t-test, one-way ANOVA followed by the Dunnett multiple comparison test, or two-way ANOVA with the Tukey multiple comparison test, as indicated

The only variable to account for this performance gain was the intravenous glutathione treatments

Liquid chromatography coupled to mass spectrometry (LCMS) HILIC chromatographic separation of metabolites was achieved using a Millipore Sequant ZIC-pHILIC analytical column (5 m, 2.1 150 mm 2 ) equipped with a 2.1 20 mm 2 guard column (both 5 mm particle size) with a binary solvent system

Prior research has demonstrated that L-theanine can reduce AGEs levels and downregulate RAGE expression in hepatic tissue, possibly through restoration of redox balance and mitochondrial function 38