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Abstract As far as my knowledge, there are no academic guidelines for diagnosis and treatment of carnitine deficiency in the world except Japan, namely, Guideline for the Diagnosis and Treatment of Carnitine Deficiency 2016 , that was published on the website of the Japan Pediatric Society in 2016 (it was revised in 2018)

Folinic acid produced significant improvements in global ADOS score, social interaction, and communication, whereas placebo showed no meaningful change (Renard et al., 2020)

L-Carnitine is an important nutrient and is necessary for fatty acid metabolism and energy production in heart and muscle function