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Quality of included reports was scored using the Jadad composite scale,13 which assesses the description of randomization, blinding, and withdrawals in the reports.14 The quality scale ranges from 0 to 5 points with a low quality report of score 2 or less and a high quality report of score at least 3.15 All discrepancies were resolved after going back to the original source papers, by consensus and involvement of a third reviewer when necessary
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Genetic associations with apolipoprotein B were obtained from UK Biobank
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It binds to the toxic glutaric acid in the bloodstream, turning it into a harmless compound that the kidneys can easily flush away in the urine [6]
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