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reported that, different from in vitro assay, as l-cysteine is present in micromolar concentrations in the intracellular environment, the activity of -glutamyl phosphate reductase (GPR) encoded by PRO2 in eukaryotes or proA in prokaryotes must be shut off to allow -GC formation from -glutamyl phosphate [12]

doi: 10.1001/jama.2020.12839 116 GeorgievaEAnanievJYovchevYArabadzhievGAbrashevHAbrashevaDet al

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4.3.2.1 Anti-apoptosis function The prevailing perspective suggests that the development of pulmonary fibrosis necessitates repetitive damage to epithelial cells and subsequent apoptosis, with documented instances of alveolar epithelial cell (AEC) apoptosis in lung fibrotic lesions (97)