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Compared with diabetic control mice, the levels of blood glucose, glycosylated hemoglobin, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) were significantly reduced in mangiferin-treated diabetic mice

In particular, the production of calpain and ceramide is altered, which can trigger eryptosis in Parkinsons disease [286, 287, 289]

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