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It pushes against it

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

Besides above oxidative stress markers of biomolecules (lipid, protein and DNA), antioxidant enzymes/molecules have been regularly used to evaluate the antioxidant defense system in human body [100]

ACS Pharmacology & Translational Science, 4 (2), 624646

Specifically, these dimers inhibit the transcription factor NF-B, which in turn controls the expression of genes related to inflammation and immunity, such as iNOS (Table 1) [7173, 75, 7779]