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A 1% topical solution applied to 100cm scalp area delivers approximately 10mg GHK-Cu per application, but percutaneous absorption of peptides is notoriously poor

Genes involved in tissue repair, collagen synthesis, and antioxidant protection see increased activity, while genes associated with inflammation, tissue breakdown, and cellular aging see reduced expression

The sublingual mucosa allows direct absorption into systemic circulation without gastric acid exposure

Le GHK-Cu is a rebuilding peptide it stimulates collagen synthesis, activates antioxidant enzymes (SOD, GPx), modulates 4,000+ genes, and repairs the extracellular matrix

Therefore, in the formulation design of skin care products, special attention needs to be paid to the control of pH value to ensure the stability and effectiveness of blue copper peptides