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Meanwhile, NNMTi preserves lean body mass: it reduces fat accumulation without causing muscle loss, which is crucial for maintaining basal metabolism and preventing weight regain after dieting.These in vivo findings fully validate the efficacy and safety of NNMTi in obesity intervention, laying a solid foundation for its subsequent clinical research and drug development

5-Amino-1MQ in research into adipose tissue metabolism Accelerated fat burning: Inhibition of NNMT leads to a reduction in 1-MNA levels (a product of NNMT activity), which promotes lipolysis the body is more inclined to mobilise fat stores

In addition to the lean and ob/ob mice, the study included 3-KO mice and WT controls obtained from genetically verified breeding colonies

Efficacy of the Autoimmune Protocol Diet for Inflammatory Bowel Disease. Inflammatory Bowel Diseases, vol

doi: 10.1016/j.tem.2017.02.004