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Nuclear factor erythroid 2-related factor 2 (Nrf2) is notably representative and is activated by NAPQI-induced redox status changes

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Western blot analysis also indicated a reduction in CXCR2 protein expression in macrophages treated with this CM (Fig

While it should be kept in mind that juvenile and adult SLE are two clinically distinct diseases 47 , in which circulating neutrophils may be likely exposed to different mediators and, eventually, function diversely, other factors might explain the differences between our results and those by Garcia-Romo and collegues 25

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