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Its dual GLP-1 and GIP receptor activation produced a 20.9% average body weight reduction at 72 weeks in the SURMOUNT-1 trial, and more recent SURMOUNT-5 head-to-head data confirmed its superiority over Semaglutide

Purposive sampling was done where an independent consultant not related to the study selected the patients for each group and another consultant assessed the patients during follow-up

Anti-RGMa antibody treatment improves hippocampal neurogenesis impairment in db/db mice Given that RGMa negatively affects the neural development of NSCs in vitro, we investigated whether the inhibition of RGMa signaling improves the reduction in DCX-positive cells and cognitive decline in diabetic mice

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Enzymatic glutathione production using metabolically engineered Saccharomyces cerevisiae as a whole-cell biocatalyst