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Vitamin B12 is important for proper digestion, and a deficiency can lead to digestive issues such as diarrhea, constipation, and loss of appetite

249,250 In vivo studies confirm mitochondrial dysfunction in high-fat diet mice, which develop neuropathy marked by reduced nerve conduction velocities and decreased IENFD

If it was exposed to heat during shipping or storage, or if it is well past its expiration date, the lyophilized powder may have undergone chemical changes that prevent proper dissolution

Furthermore, the aforementioned study put to rest the idea that antivirals can be used in combination with steroids to treat Bells palsy

Vitamin B12 is a cofactor in the enzymatic reaction that converts MMA to succinyl-CoA, and B12 and folic acid are co-factors in the reaction that converts homocysteine to methionine