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Vuong L, Kotecha RR, Voss MH, Hakimi AA

injection of ligand clozapine N-oxide (CNO, Sigma, C0832) or Deschloroclozapine dihydrochloride (DCZ, MCE, HY-42110)

The paper, by joint first authors Malik YM, Guo F et al., and titled: 'Impaired striatal glutathioneascorbate metabolism induces transient dopamine increase and motor dysfunction', is published in Nature Metabolism and can be viewed at: With associated Research Briefing that can be found at: And University of Oxford press release: Discovery of key mechanism in Huntingtons Disease could pave the way