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These modifications have been hypothesized to play a crucial role in the diffusion of DNA damage response/senescence-associated secretory phenotype (DDR/SAPS) signaling to non-damaged surrounding cells during aging, suggesting that DDR/SASP signaling components may contribute to the development of novel therapeutic interventions against age-related diseases (Olivieri et al., 2015)

The conjugation reaction was performed by incubating 0.1 mg/mL GSH with 1 M Rhodamine B in PBS for 2 h at room temperature

[12] Your healthcare provider will determine the appropriate schedule based on your specific needs and response to treatment

This results in increased unstable iron pools and promoted lipid peroxidation

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