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As a treatment for facial paralysis, especially synkinesis, BOTOX treats a variety of conditions, including: Excessive muscle tightness around the eye (blepharospasm) Excessive and constant facial muscle contraction (facial spasticity or hypertonicity) Involuntary facial movement (synkinesis), most commonly oral-ocular synkinesis, in which the eye closes when attempting to smile or eat or ocular-oral synkinesis, in which the mouth moves when attempting to close the eye

Sympathetic overdrive, which may occur from stress, anxiety, panic disorder, hypoglycemia, and hypoxia

RNovA enables exploration of previously inaccessible regions of the proteome, including peptides with unexpected or unannotated modifications

Claims submitted for coverage under publicly funded programs (e.g

2024 Feb;78(2):155-162