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PLoS ONE 8 , e74538 (2013)

Liver transplantation can cure the disease and may be lifesaving for people who have Wilson disease and severe liver failure or severe liver problems that do not respond to drug treatment.

Moreover, NTAPP did not induce significant apoptosis which was verified by flow cytometry and quantitative RT-PCR (qRT-PCR) for apoptosis-related genes (Supplementary Figure 1b, 1c)