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As SNpc DA neurons are scarcely or thinly myelinated, very few transplantation studies dealing with this neuronal population have assessed whether the grafts acquire myelination or affect the host OL population

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The central innovation of POPE 13 C-MRS is the detection of heteronuclear 1 H- 13 C satellite resonances using targeted proton editing, enabling the simultaneous measurement of 13 C-labelling of metabolites such as glutamate, GABA and lactate while avoiding broadband 13 C excitation or decoupling