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In summary, the synthesis of melanotan peptide using chemical synthesis requires multiple chemical reaction and purification steps, and the reaction conditions and operating processes of each step need to be strictly controlled to ensure the purity and yield of the final product

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Where a co-existing diabetic complication has no dedicated subcode of its own, it is captured with the other specified diabetic complication code E11.69, which still requires an additional code naming the specific condition

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PMC 5930388