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Roles of Resveratrol and Other Grape-Derived Polyphenols in Alzheimer's Disease Prevention and Treatment

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Second, during energy metabolism, mitochondria produce ROS and other free radicals that can accumulate excessively and damage cell membranes, proteins, and DNA, thereby accelerating neuronal degeneration (Swerdlow, 2018)

Oct 1 2022;364:9-15

This manuscript provides deeper insight into the pathophysiology of PD, various drug delivery strategies to overcome BBB, and the potential role of nanoemulsions via the intranasal route