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Grettano opened by explaining that the Ignatian Year allowed her to reflect on how the process has changed her life, including the way she responded to a 2015 breast cancer diagnosis

Transcriptomic analysis revealed significant differences between expression signatures of Nrf2 WT and KO cells, showing 1,566 up-regulated and 5,272 down-regulated genes in the Nrf2 KO condition compared with the WT (Fig 6A)

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Running distance, food intake and body weight were measured daily before dosing of experimental compounds