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Oxidative stress is associated with excess copper ions, while copper ion deficiency affects the association between copper and the mitochondria, as well as copper and vascular regulation (36)

PMID: 64 MoserGHSchraderJDeussenA

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Additionally, we identify the FHA domain of SNIP1 as a reader of P-SF3B1, guiding the recruitment and assembly of the RES complex during spliceosome activation, and show that mutations in the FHA domain, including the neurodevelopmental disorder-linked E366G variant, impair this interaction, resulting in defects in splicing and cellular proliferation

The section below discusses the scope of the dermal therapeutic approach against skin cancer