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Collectively, these findings demonstrate that psychological trauma initiates a cascade of interconnected MGBA disruptions in PTSD, encompassing HPA axis dysregulation, microbial dysbiosis, compromised gut barrier integrity, chronic inflammation and neurotransmitter imbalances across serotonergic, dopaminergic, and GABAergic systems

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Currently, cagrilintide remains investigational and available only as a research chemical while awaiting FDA approval expected 2025-2026

Braunstein,M., Sobel,R