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Future research is needed to clarify the optimal doses of tPBM, particularly for nonwhite patients who may require higher treatment doses due to greater light absorption losses by higher levels of skin melanin, which reduces the penetration of light into brain tissues

Concordance test between self-reported and diagnosed diabetic retinopathy showed a Kappa coefficient of 0.30 (95%CI, 0.13 0.47), in which 16.5% of the participants reported having no diabetic retinopathy despite being diagnosed as having it

This protects the peptide from rapid clearance and extends its half-life

Numerous antioxidant hydrogels have been developed and proven effective in alleviating oxidative stress

The substantial increase in intracellular levels of ROS supports these findings