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Paradoxically, this more reducing redox environment correlated with increases in mitochondrial oxidation and cell death, suggesting that elevated GSH levels result in reductive stress and cytotoxicity (117)

The CCK-8 assay was initially performed to assess the in vitro cytotoxicity of NFX

11 The team of Jens Juul Holst at the University of Copenhagen in Denmark published a report in FEBS Letters, reaching the same conclusion in January 1987

The disease is progressive, and the symptoms usually get worse overtime

Resveratrol converses multidrug resistance and sensitizes cancer cells to common chemotherapeutic agents