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ACS Med Chem Lett 11:706712

Specifically, it significantly enhances the malignant potential of tumor cells under extreme conditions, such as hypoxia and acidosis, by inducing genomic instability, activating oncogenic signaling pathways, and remodeling the TME

observed that MG inhibits NF-B activation by directly suppressing the binding of NF-B p65 to DNA (111)

16-OH-E2 (also known as E3, or estriol) is a safer estrogen metabolite, as it is a very weak estrogen and may have protective properties

Here are some examples of peptide bonds in DNA: Histone proteins are positively charged due to the presence of basic amino acids (arginine and lysine) and are essential for maintaining the structure of DNA