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The American Academy of Family Physicians and NIH identify the following clinical manifestations: Fatigue and generalized weakness Megaloblastic anemia (abnormally large, immature red blood cells) Tingling or numbness in the hands and feet (peripheral neuropathy) Difficulty walking and balance problems Cognitive disturbances including memory difficulty and confusion Mood changes, including depression and irritability Glossitis (swollen, inflamed tongue) Early symptoms such as fatigue and mild tingling are often attributed to stress, aging, or other conditions

Also, the phenolics increase the effectiveness of the insulin hormone by facilitating the signaling (IRS-1/Akt) and the movement (GLUT4 translocation) of the glucose transporter (GLUT4) located inside the cell

Sermorelin is generally well tolerated, with most side effects being mild and temporary