lipid peroxidation hepatitis c virus+ drug resistance Metabolic complications of virus infection Core Concepts - Extrahepatic Conditions

The brain is particularly susceptible to oxidative stress due to its high oxygen consumption, rich lipid content, and comparatively limited antioxidant capacity, making redox imbalance a salient contributor to neuronal dysfunction within depressive pathophysiology (3537)

For inhibition of thioredoxin reductase or glutathione reductase activity, cells were subsequently treated with 1 M auranofin (Sigma Aldrich, Darmstadt, Germany) or 50 M 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) (Sigma Aldrich, Darmstadt, Germany) respectively for 1 h

Konopleva M, Estrov Z, Monaco G, Tsao T, Sporn M, Andreeff M

A., Wu, X., Ji, K., Gao, Q., Xin, G., Cong, H., & Yang, G

Each tablet contains 25 mg of L-glutathione