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The discovery of protein aggregates and causative mutations in FUS/TLS 2,3 and TDP-43 (refs 4, 5, 6, 7), two strikingly similar RBPs, as dominant causes of both the fatal adult motor neuron disease amyotrophic lateral sclerosis (ALS) and the second most frequent degenerative cognitive disorder (frontal temporal degeneration (FTD)) has initiated a paradigm shift in research on this pair of diseases, with errors in RNA maturation now a focus as a central component of disease mechanism 1,2,3,4,5,6,7,8

11 Biological roles and mechanism of phytochemicals in disease prevention and treatment

Cancer 136 (3), 699708

In todays hectic world, stress, environmental pollution and internal toxins all take their toll

My timeline tracked close to that