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Follow aseptic technique and use new sterile equipment for each administration

IGFBP-3 proteolysis has also been described in insulin resistant states such as fasting, obesity and type 1 and 2 diabetes (62, 124, 125)

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However, recent work suggests that lipolysis may not be linear, as many of the protein players involved in adipocyte lipolysis are multifunctional enzymes able to catalyze reactions in both directions (20-22), resulting in the re-esterification and recycling of FAs (23), thereby challenging the current model