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965 Combined with DFP, SLN124 is more effective in reducing liver iron overload than treatment alone, representing a promising pharmacological therapy for the treatment of ferroptosis-related diseases

These events drive aberrant protein aggregation, proteotoxic stress, mitochondrial dysfunction, and energetic collapse, culminating in cell death

10.1038/nrneph.2013.98 25 NaitoY.FujiiA.SawadaH.OboshiM.IwasakuT.OkuharaY.et al (2015)

2.12.1 Therapeutic investigations BALB/c mice have served as an invaluable model for investigating the therapeutic potential of natural compounds in AD research