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Through this cycling, Arfs recruit coat proteins (e.g., clathrin), coat adaptor proteins, cargoes, lipid-modifying enzymes, and cytoskeletal regulators to budding vesicles [112]

While the workflow has been systematically applied across multiple patients, this case exemplifies how exome sequencing, PRS calculation, and biochemical profiling can converge into a consolidated report and ultimately a targeted clinical plan

There is not as much evidence regarding long-term efficacy or safety of gel vitamin B12 compared to injections, but at this time it appears B12 gel works similarly to raise blood levels

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