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Additionally, cocaine induces the expression of endothelin-1, a peptide with strong vasoconstrictive properties [16, 17]

Shimizu M, Individual differences of drug-metabolizing enzymes as determinants for the metabolic fate of chemicals--A study of trimethylamine and flavin-containing monooxygenase 3-10.1248/yakushi.129.1351 [Google Scholar] [CrossRef] [21]