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5 combined L-BSO with sulphasalazine or auranofin (a gold salt used in the treatment of rheumatoid arthritis) to inhibit both glutathione- and thioredoxin-dependent antioxidant pathways, triggering synergistic cancer cell death (Fig

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2.7 Cell uptake For verifying the effect of PEGylation on NP internalization efficiency, PEG-coated and uncoated Cy5-labeled ps-PAAQ NPs were incubated with C28/I2 cells in a 35 mm glass-bottom dish (CELLview), during 3 h at 37C

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