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Many proteins are associated with ALS pathogenesis, and mutations in the genes encoding them usually deepen and accelerate LLPS and eventually form fibril aggregates 51,52,53,54,55,56,57

Oncol Rep 47:60

10.3390/biomedicines10123285 103 PatelD.SharmaD.MandalP

The human AdhC homolog ADH3 is particularly well characterized

Recent work has also begun to decipher the specific pathways and sub-cellular compartments that are important for one-carbon metabolism in cancer cells