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Its all too common for patients to suffer in silence for years before seeking treatment

47 EkhtiariH.TavakoliH.AddoloratoG.BaekenC.BonciA.CampanellaS.et al (2019)

doi: 10.1038/s41590-022-01244-9

After 1 month of treatment in pernicious anemia patients, the once weekly dosing of 500 mcg B12 intranasal gel resulted in a statistically significant increase in B12 levels when compared to a once monthly 100 mcg IM dose

La vitamine B 12 est absorbe au niveau de l'ilon terminal par deux mcanismes: un mcanisme passif lorsque les quantits sont importantes, et un mcanisme actif qui permet l'absorption des doses physiologiques et pour lequel la prsence du facteur intrinsque est indispensable